Crystal structure of the c-Met kinase domain in complex with a pyrazolone inhibitor
收藏Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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Crystal structure of the c-Met kinase domain in complex with a pyrazolone inhibitor Descriptor: Hepatocyte growth factor receptor, N-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide Authors: Bellon, S.F, Whittington, D.A, Long, A.M. Deposit date: 2016-08-26 Release date: 2016-09-21 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of AMG337: Using structure guided scaffold hydridization to optimize physicochemical properties and target coverage of a MET kinase inhibitor to be published
创建时间：
2016-08-26
