WEHI-601 resistant parasites contain a mutation in Plasmepsin V
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP166467
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资源简介：
Resistance of P. Falciparum wildtype parasites were raised to peptidomimetic inhibitor, WEHI-601. These parasites were cloned and whole genome sequenced which revealed a SNP in the aspartyl protease Plasmepsin V (T371P) in both clones. This confirmed the on-target activity of the peptidomimetic series against PMV.
创建时间：
2025-02-01
