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Aurora-2 T287D T288D complexed with PHA-680632

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Protein Data Bank Japan2024-05-01 更新2026-03-21 收录
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Aurora-2 T287D T288D complexed with PHA-680632 Descriptor: (3E)-N-(2,6-DIETHYLPHENYL)-3-{[4-(4-METHYLPIPERAZIN-1-YL)BENZOYL]IMINO}PYRROLO[3,4-C]PYRAZOLE-5(3H)-CARBOXAMIDE, SERINE THREONINE-PROTEIN KINASE 6 Authors: Cameron, A.D, Izzo, G, Sagliano, A, Rusconi, L, Storici, P, Fancelli, D, Berta, D, Bindi, S, Catana, C, Forte, B, Giordano, P, Mantegani, S, Meroni, M, Moll, J, Pittala, V, Severino, D, Tonani, R, Varasi, M, Vulpetti, A, Vianello, P. Deposit date: 2005-03-11 Release date: 2005-03-17 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Potent and Selective Aurora Inhibitors Identified by the Expansion of a Novel Scaffold for Protein Kinase Inhibition. J.Med.Chem., 48, 2005
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2005-03-11
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