Different gene expression of Musashi1 gene overexpression in mouse skin

To further understand expression patterns of musashi1 overexpression (DTG) in mouse skin,we have employed microarray expression profiling as a discovery platform to identify different genes expression with DTG mouse and Control mouse. Comparision with Control mouse,upgene is 3772 in DTG mouse, downgene is 5529. mTOR pathway, RAS pathway, PI3K-AKT pathway,IL6-JAK-Stat3 pathway and so on are activated, WNT Pathway is inhibited. 4 Control mouse skin and 4 DTG mouse skin were taken and immediately put it to -80 Refrigerator.Trizol was added to the samples,RNA were extracted with trizol according to instructions,Good quality RNA were explored as microarrary analysis in capitalBio technology.