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Crystal structure of human CYP3A4 bound to an inhibitor

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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资源简介:
Crystal structure of human CYP3A4 bound to an inhibitor Descriptor: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, S-{(2S)-2-[(1-tert-butoxyethenyl)amino]-3-phenylpropyl}-N~2~-cyclopentyl-N-[(pyridin-3-yl)methyl]-L-cysteinamide Authors: Sevrioukova, I. Deposit date: 2017-10-21 Release date: 2017-12-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Interaction of the rationally designed ritonavir-like inhibitors with human cytochrome P450 3A4: Impact of the side group interplay Mol. Pharm., 2017
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2017-10-21
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