eIF4E hypersensitive mRNA translation is characterized by long and structured untranslated regions

ChEBI2015-12-31 更新2026-07-12 收录

mRNA翻译调控

非翻译区结构分析

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eIF4E hypersensitive mRNA translation is characterized by long and structured untranslated regions

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2015-12-31

Translational repression of the Drosophila nanos mRNA involves the RNA helicase Belle and RNA coating by Me31B and Trailer hitch

果蝇生物学

mRNA翻译调控

The maternal mRNA nanos is required for anterior-posterior patterning in the early Drosophila melanogaster development. The nanos-mRNA is translationally repressed and deadenylated during the first tw

NIAID Data Ecosystem90

GCN2 suppresses TOP mRNA translation via LARP1

mRNA翻译调控

营养应激信号通路

La-related protein 1 (LARP1) has been identified as a key translational inhibitor of terminal oligopyrimidine tract (TOP) mRNAs downstream of the nutrient sensing protein kinase complex, mTORC1. LARP1

NIAID Data Ecosystem40

The CCR4-NOT complex suppresses untimely translational activation of maternal mRNAs.

卵母细胞成熟

mRNA翻译调控

Control of mRNA poly(A) tail has central role to regulate mRNA metabolism: translation efficiency and mRNA stability. Gene expression in maturing oocytes largely relies on the regulation of mRNA metab

Alliance of Genome Resources20

Co-transcriptional pseudouridylation of mRNAs by the H/ACA complex controls translational efficiency [ChIP-seq]. Co-transcriptional pseudouridylation of mRNAs by the H/ACA complex controls translational efficiency [ChIP-seq]

mRNA翻译调控

假尿苷修饰机制

Post-transcriptional modifications of mRNA have emerged as novel regulators of gene expression. Pseudouridylation is the most abundant and widespread type of RNA modification in living organisms; howe

NIAID Data Ecosystem80

RGG motif-containing Scd6/LSM14A proteins regulate the translation of specific mRNAs in response to hydroxyurea-induced genotoxic stress

基因毒性应激响应

mRNA翻译调控

RGG motif-containing proteins are the second largest group of RNA-binding proteins. Here, we identify a unique and conserved role of yeast Scd6 and its human ortholog LSM14A in hydroxyurea (HU)-mediat

NIAID Data Ecosystem20

eIF4E hypersensitive mRNA translation is characterized by long and structured untranslated regions

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