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RNA seq with AML (NB4) cells upon FTO inhibition

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NIAID Data Ecosystem2026-04-30 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP116934
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To determine the potential targets of FTO and identify treatment significance of FTO inhibition in AML, we conducted transcriptome wide RNA seq with NB4 cells upon DMSO and FTO inhibitors (FB23 and FB23-2) treatment. Overall design: NB4 cells were treated with FB23, FB23-2 and DMSO for 48 hours. Total RNA were isolated from the harvested cells and poly(A)+ RNA were enriched with NEBNext Poly(A) mRNA Magnetic Isolution Module. RNA-seq was performed on Illumina Hiseq system.
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2023-01-11
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