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Crystal structure of human farnesyl pyrophosphate synthase in complex with a cryptic pocket ligand, JDS05120

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Protein Data Bank Japan2026-04-08 更新2026-04-25 收录
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Crystal structure of human farnesyl pyrophosphate synthase in complex with a cryptic pocket ligand, JDS05120 Descriptor: Farnesyl pyrophosphate synthase, PHOSPHATE ION, [({5-[4-(cyclopropyloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic acid) Authors: Pandya, V.R, Park, J. Deposit date: 2024-08-01 Release date: 2025-10-29 Last modified: 2026-04-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery and computational characterization of a novel cryptic pocket in human farnesyl pyrophosphate synthase. J.Struct.Biol., 2026
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2024-08-01
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