TGF- and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance.

Alliance of Genome Resources2026-08-01 收录

生殖衰老

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TGF- and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance.

Supplementary Material for: Total flavonoids of Polygala fallax Hemsl induce apoptosis of human ectopic endometrial stromal cells through PI3K/AKT/Bcl-2 signaling pathway

细胞凋亡

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Abstract Objective: to explore the inhibitory effect of total flavonoids of Polygala fallax Hemsl (PFHF) on human ectopic endometrial stromal cells (HEcESCs) and its mechanism. Design: The potential t

DataCite Commons2023-06-20 更新60

TGF-β Inducible Early Gene 1 Regulates Osteoclast Differentiation and Survival by Mediating the NFATc1, AKT, and MEK/ERK Signaling Pathways

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细胞生物学

TGF-β Inducible Early Gene-1 (TIEG1) is a Krüppel-like transcription factor (KLF10) that was originally cloned from human osteoblasts as an early response gene to TGF-β treatment. As reported previous

NIAID Data Ecosystem40

Cadmium induces CCL2 production in glioblastoma cells via activation of MAPK, PI3K, and PKC pathways

胶质母细胞瘤

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Cadmium (Cd) is accumulated in human astrocytes and induces the production of interleukin (IL)-6 and IL-8. Astrocytes are one of the major sources of chemokine C–C motif ligand 2 (CCL2; known as monoc

DataCite Commons2021-05-07 更新40

DataSheet_2_Chenodeoxycholic Acid Enhances the Effect of Sorafenib in Inhibiting HepG2 Cell Growth Through EGFR/Stat3 Pathway.xlsx

癌症治疗

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BackgroundHepatocellular carcinoma (HCC) is a highly invasive disease with a high mortality rate. Our previous study found that Chenodeoxycholic acid (CDCA) as an endogenous metabolite can enhance the

NIAID Data Ecosystem40

Additional file 3 of Iguratimod suppresses Tfh cell differentiation in primary Sjögren’s syndrome patients through inhibiting Akt/mTOR/STAT3 signaling

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药物靶点预测

Additional file 3: Supplementary Table S3. Target prediction of iguratimod.

DataCite Commons2024-08-15 更新40