Expression profiling, U2OS, Aurora kinase and p38 inhibitor response

ChEBI2017-07-01 更新2026-07-12 收录

激酶抑制剂

白细胞表达谱分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-1210 数据链接链接失效反馈

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Expression profiling, U2OS, Aurora kinase and p38 inhibitor response

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2017-07-01

Optimization of a Novel Series of Ataxia-Telangiectasia Mutated Kinase Inhibitors as Potential Radiosensitizing Agents

激酶抑制剂

放射增敏剂

We previously reported a novel inhibitor of the ataxia-telangiectasia mutated (ATM) kinase, which is a target for novel radiosensitizing drugs. While our initial lead, compound 4, was relatively poten

NIAID Data Ecosystem70

Wee1 inhibition in acute lymphoblastic leukemia with MLL rearrangement.

白血病表观遗传学

激酶抑制剂

Enhancer activity and RUNX1 binding was studied using ChIP-seq in mixed lineage leukemia t(4;11) rearranged acute lymphoblastic leukemia upon inhibition of the WEE1 kinase. Overall design: ChIP-seq pr

NIAID Data Ecosystem10

An epigenetic signature of developmental potential in neural stem cells and early neurons [expression]

发育表观遗传调控

白细胞表达谱分析

An epigenetic signature of developmental potential in neural stem cells and early neurons [expression]

ChEBI2013-06-09 更新00

Synthesis of the Kinase Inhibitors Nintedanib, Hesperadin, and Their Analogues Using the Eschenmoser Coupling Reaction

激酶抑制剂

Eschenmoser偶联反应

A novel synthetic approach involving an Eschenmoser coupling reaction of substituted 3-bromooxindoles (H, 6-Cl, 6-COOMe, 5-NO2) with two substituted thiobenzanilides in dimethylformamide or acetonitri

Figshare2021-07-16 更新10

Crystal structure of human Cdk12/Cyclin K in complex with the inhibitor BSJ-01-175

结构生物学

激酶抑制剂

Crystal structure of human Cdk12/Cyclin K in complex with the inhibitor BSJ-01-175 Descriptor: (E)-N-[4-[(1R,3R)-3-[[5-chloranyl-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]cyclohexyl]oxyphenyl]-4-(dimethyl

Protein Data Bank Japan2025-10-01 更新10

Expression profiling, U2OS, Aurora kinase and p38 inhibitor response

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