In this study, we generated zebrafish pld6 knockouts and found that the pld6-null mutants developed as infertile males, with testes containing no germ cells. Pld6 is considered to be a candidate ribon

NIAID Data Ecosystem130

An Ancient Transcription Factor Initiates the Burst of piRNA Production During Early Meiosis in Mouse Testes (RNA-Seq)

piRNA生物合成

精子发生

Animal germ cells produce PIWI-interacting RNAs (piRNAs), small silencing RNAs that suppress transposons and enable gamete maturation. Mammalian transposon-silencing piRNAs accumulate early in spermat

NIAID Data Ecosystem80

ADAD2 facilitates piRNA biogenesis and spermiogenesis in mice

piRNA生物合成

精子发生

Adenosine Deaminase Domain Containing 2 (ADAD2) is a testis-specific protein composed of a double-stranded RNA binding domain and a non-catalytic adenosine deaminase domain. A recent study showed that

NIAID Data Ecosystem50

An Ancient Transcription Factor Initiates the Burst of piRNA Production During Early Meiosis in Mouse Testes (RNA-Seq)

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