首页/数据集/Variant PRC1 complex dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation

Variant PRC1 complex dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation

ChEBI2014-05-27 更新2026-07-21 收录

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数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-55698 数据链接链接失效反馈

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Variant PRC1 complex dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation

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2014-05-27

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To examine if loss of FIS1 would alter the H3K27Ac status of leukemic cells, we used shRNA to knock down the expression of FIS1 in leukemic cell line MOLM-13 cells and performed H3K27Ac CHIP-seq to ch

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The abnormal tumor vasculature can present a barrier to the infiltration of anti-tumor immune cells, which impairs immune surveillance and response to immunotherapy. Here, we show that targeting the e

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Variant PRC1 complex dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation

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