Exploring Antibiotic Resistance in Diverse Homologs of the Dihydrofolate Reductase Protein Family through Broad Mutational Scanning

This compressed zip file contains the of DHFR (variant-barcode) mapping and NGS barcode count files used in the RMD analysis scripts for the publication: <i>Exploring antibiotic resistance in diverse homologs of the dihydrofolate reductase protein family through broad mutational scanning</i>Karl J. Romanowicz et al. , Sci. Adv.11,eadw9178(2025). DOI:10.1126/sciadv.adw9178<br><br>The RMD analysis scripts are available here:<br>https://github.com/PlesaLab/DHFR<br><br>The folder structure within the zip file matches the RMD loading calls.<br>Additional links:<b>RPubs:</b> Rendered Code<b>NCBI BioProject:</b> PRJNA1189478 for raw .fastq files<br><br>FigShare Repository: Processed DHFR fitness scores.<br>