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REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer
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Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Prostate Cancer Cells
Androgen receptor (AR) signaling pathway remains the foremost target of novel therapeutics for castration-resistant prostate cancer (CRPC). However, the expression of constitutively active AR variants
NIAID Data Ecosystem60
ERG-mediated coregulator complex formation maintains androgen receptor signaling in prostate cancer [PolII ChIP]
We report the effects of ERG on prostate tumorigenesis, ERG-mediated oncogene addiction, and downstream AR signaling pathways. We determined that ERG facilitates AR-signaling and mediates transformati
NIAID Data Ecosystem30
RNAseq PC3 DMSO vs GW3965. RNAseq PC3 DMSO vs GW3965
Identify LXR target gens that are involved in migration and invasion phenotype Overall design: PC3 prostate cancer cell were treated for 24h with DMSO or GW3965 1µM in RPMI-1640, L-Glu 2mM after overn
NIAID Data Ecosystem10
Genomic copy number alterations as predictive markers of systemic recurrence in breast cancer
Genomic copy number alterations as predictive markers of systemic recurrence in breast cancer
ChEBI2010-05-26 更新30
Circular RNA hsa_circ_0075542 acts as a sponge for microRNA-1197 to suppress malignant characteristics and promote apoptosis in prostate cancer cells
Numerous differentially expressed circular RNAs (circRNAs) have been identified; however, their roles have not been fully elucidated. Since dysregulated circRNAs may have clinical applications, it is
Taylor & Francis Group2024-02-20 更新10
