FXR ACTIVATION REMODELS TRANSCRIPATION LANDSCAPE AND GUT-LIVER CROSSTALK IN NON-ALCOHOLIC STEATOHEPATITIS
收藏NIAID Data Ecosystem2026-05-01 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1020276
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资源简介：
The mechanisms by which FXR-mediated gut-liver axis contributes to NASH resolution are insufficiently elucidated. This study collected transcriptomic data from the liver and intestine after Fxr knockdown superimposed on OCA treatment. Livers from Fxrf/f, Fxr-IE-knockdown, Fxrf/f+OCA and Fxr-IE-knockdown +OCA mice. Intestine from Fxrf/f+OCA and Fxr-Hep-knockdown +OCA mice. This study provides novel insights into FXR-mediated gut-liver axis contributes to NASH resolution.
创建时间：
2023-09-23
