Read statistics for sequence data and assembly of suppressor strain genomes.

“Total Reads” indicates the number of 36-nt reads generated for each strain by Illumina GAII sequencing. “Aligned Reads” indicates the proportion of the total reads that were reliably aligned to the reference sequence. “Suppressed Reads” are reads that were excluded from the completed alignment because of regions of poor quality or because they aligned to more than one region of the genome. “Orphan Reads” are the proportion of the total reads that failed to align to the reference, most often due to very poor quality at the ends of the read. “Approximate Genome-Wide Depth of Aligned Coverage” is the average number of reads that aligned to each nucleotide in the genome, indicated the number of data points mapped for each nucleotide.