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Mechanistic study of Wee1 kinase inhibition with AZD1775 exposes drug targetable vulnerabilities in acute B-lymphoblastic leukemia [GROseq]. Mechanistic study of Wee1 kinase inhibition with AZD1775 exposes drug targetable vulnerabilities in acute B-lymphoblastic leukemia [GROseq]

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA908801
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Nascent transcription and enhancer activity was studied using GRO-seq in the acute lymphoblastic leukemia cell line RS4;11 upon inhibition of the WEE1 kinase. Overall design: GRO-seq profiles were generated from RS4;11 cell line after 4, 10 and 24 h WEE1 inhibition by AZD1775. DMSO treated cells were used as controls.
创建时间:
2022-12-05
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