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An Intramolecular [2 + 2] Cycloaddition of Ketenimines <i>via</i> Palladium-Catalyzed Rearrangements of <i>N-</i>Allyl-Ynamides

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NIAID Data Ecosystem2026-03-07 收录
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A cascade of Pd-catalyzed N-to-C allyl transfer–intramolecular ketenimine–[2 + 2] cycloadditions of N-allyl ynamides is described. This tandem sequence is highly stereoselective and the [2 + 2] cycloaddition could be rendered in a crossed or fused manner depending on alkene substitutions, leading to bridged and fused bicycloimines.

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2012-06-15
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