Resulting samples for the expected utility of the three alternatives

The data displayed in this file are the resulting samples for the expected utility of the three considered treatment alternatives in all considered scenarios. They have been obtained by combining the data displayed in the two files 'Sampled values for all probability variables of the benefit-risk assessment' and 'Sampled values for all utility variables of the benefit-risk assessment', using the decision tree depicted in Figure 3 and the formulae given in Figure 1. The first four columns are used to determine what scenario of the assessment that is considered: the first column indicates the type of distribution over the derived risk intervals for the serious adverse effects; the second column indicates the proportion of the sampled risk values that is attributed to the background; the third column indicates the severity of the relapse as measured by the patient's starting EDSS value; and the fourth column indicates the so called minimum utility difference between lethal and non-lethal outcomes. The fifth, sixth, and seventh columns then show the computed expected utility values for high-dose methylprednisolone (HDMP), low-dose methylprednisolone (LDMP), and no treatment (NT), respectively. There are 10,000 rows for each scenario.