X-ray crystal structure of human anaplastic lymphoma kinase in complex with CH5424802
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X-ray crystal structure of human anaplastic lymphoma kinase in complex with CH5424802 Descriptor: 1,2-ETHANEDIOL, 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile, ALK tyrosine kinase receptor Authors: Nagel, S, Moertl, M, Jestel, A, Fukami, T.A. Deposit date: 2010-10-08 Release date: 2011-05-25 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant Cancer Cell, 19, 2011
创建时间:
2010-10-08



