STED images of IR-induced 53BP1/RAD18 foci in U2OS cells

NIAID Data Ecosystem2026-05-02 收录

DNA损伤修复

超分辨率成像

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https://www.omicsdi.org/dataset/biostudies-other/S-BSST1239 数据链接链接失效反馈

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STED images of IR-induced RAD18 foci in U2OS cells and 53BP1 foci in parental U2OS and U2OS-RAD18-KO cells

创建时间：

2024-05-23

Shielded-PAINT data analysis files

超分辨率成像

生物医学成像

Data and analysis scripts for Shielded-PAINT imagingThe data and analysis scripts provided in this repository are to accompany a manuscript about Shielded-PAINT super-resolution imaging. This manuscri

DataCite Commons2025-05-23 更新80

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients.

皮肤癌突变谱

DNA损伤修复

The UV component of sunlight is the major carcinogen involved in the etiology of skin cancers. We have studied the rare, hereditary syndrome xeroderma pigmentosum (XP), which is characterized by a ver

PubMed Central1993-11-15 更新40

Electrochemically controlled switching of dyes for enhanced super-resolution optical fluctuation imaging (EC-SOFI)

超分辨率成像

荧光染料电化学控制

In super-resolution optical fluctuation imaging (SOFI), molecules spaced closer than the diffraction limit can be identified through spatial and temporal correlation analysis of the fluorescence int

DataCite Commons2026-03-12 更新50

Data and code for analyzing DSB mobility

DNA损伤修复

肌动蛋白动力学

Double-strand breaks (DSBs) are critical lesions in genomic DNA, and their accurate repair is essential for maintaining genome stability. The nuclear actin cytoskeleton has been implicated in homology

DataCite Commons2025-10-22 更新40

STED images of IR-induced 53BP1/RAD18 foci in U2OS cells

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