BIOGRID CURATED DATA FOR ELO2 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for ELO2 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway; ELO2 has a paralog, ELO1, that arose from the whole genome duplication

针对酿酒酵母（S288c）的ELO2蛋白-蛋白、遗传及化学相互作用数据集，由BioGRID（https://thebiogrid.org）精心编纂；定义：脂肪酸延长酶，参与鞘脂生物合成过程；作用于碳链长度达24个碳原子的脂肪酸；突变对1,3-β-葡萄糖合酶、溶酶体ATP酶及分泌途径具有调控作用；ELO2存在一个同源基因ELO1，该同源基因起源于全基因组倍增。