Economic parameters (2010 US $).

*Estimated using the bill sizes per dengue patient and day. The distribution was truncated to only positive values.†Average daily ridership and average round trip distance used to calculate weighted average transportation cost. It includes Mass Rapid Transport and Light Rapid Transport systems, bus, and taxi. An average of two family visits per day per inpatient are assumed. Transport in Singapore is not subsidized [66].§Includes the costs and proportion of patients tested using dengue PCR ($111.5) or serology tests ($25.9) in the first consultation , medical officer consultation fees ($30.9 for first consultation and $24.3 subsequent consultations), cost of full blood count in all consultations ($16.4), urea ($6.7), protein ($7.1), ALT ($7.1) and AST ($7.1) tests and cost of symptoms relief medicaments ($6.6 including paracetamol for fever, metocloperamide for vomiting, peritoh for itch and famotidine for gastric irritation).‡Obtained by dividing the GDP per capita by the working days per year. The productivity loss by an undetermined day of work is obtained by dividing the GDP per capita by 365 days.¢Due to lack of data on allocation of hours to household activities in Singapore, we employ US cost data expressed in US 2010 $. In the model we distinguish the household service losses per day in the age groups: 15–17 ($15), 18–29 ($26), 30–64 ($40), 65–74 ($45) and >75 ($38).¥Families in this situation are assumed to be families with all working parents, without maid and without unemployed or retired family members available to give care to the children. The proportion of children belonging to families where nobody cooks at home is used as a surrogate for these families [64] . For the rest of the families, the care giver is imputed a cost corresponding to the household services that cannot be carried out during the time of care giving.¶The estimate corresponds to the number of persons >65 years old living alone. A social worker with a salary of $13/hour is assumed to be hired as care giver 8 hours a day. For the rest of elderly the care givers are imputed a cost equal to their household services.∥Average government expenditure divided by total number of primary or secondary students and total school days.††Low effectiveness as compared to previous studies assuming 95% [53] to reflect the difficulty of obtaining a vaccine for the four serotypes.◊Corresponds to Panama in [52] .