Structure of (R)-naproxen bound to mCOX-2.

Protein Data Bank Japan2026-08-12 更新2026-03-21 收录

COX-2-萘普生复合物结构

底物选择性抑制机制

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Structure of (R)-naproxen bound to mCOX-2. Descriptor: (2R)-2-(6-methoxynaphthalen-2-yl)propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... Authors: Duggan, K.C, Hermanson, D.J, Musee, J, Prusakiewicz, J.J, Scheib, J, Carter, B.D, Banerjee, S, Marnett, L.J. Deposit date: 2011-01-04 Release date: 2011-11-09 Last modified: 2026-08-12 Method: X-RAY DIFFRACTION (2.4 Å) Cite: (R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2. Nat.Chem.Biol., 7, 2011

创建时间：

2011-01-04

Structure of (R)-naproxen bound to mCOX-2.

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