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NgTET1 in complex with 5hmC DNA
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2023-09-27
相关数据集
UHRF2 Commissions the Accomplishment of DNA Demethylation through Allosteric Activation by 5hmC and K33-linked Ubiquitination of XRCC1
The transition of oxidized 5-methylcytosine (5mC) intermediates into base excision repair (BER) pipeline to complete DNA demethylation remains enigmatic. We report here that UHRF2, the only paralog of
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Fam60a is a component of the mSin3A-HDAC transcriptional corepressor complex and inhibits Tet-mediated DNA demethylation
Fam60a was identified as a highly expressed gene of unknown function in mouse embryonic stem cells. We have examined the role of Fam60a in mouse development. Most Fam60a mutant embryos manifest hypopl
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Monotherapy of the DNA Hypomethylating Agent, NTX301 Targets Ovarian Cancer. Monotherapy of the DNA Hypomethylating Agent, NTX301 Targets Ovarian Cancer
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
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Active DNA demethylation promotes cell fate specification and the DNA damage response [SEAL]
Neurons harbor high levels of endogenous single strand DNA breaks (SSBs) that are targeted to neuronal enhancers and correlate with marks of DNA demethylation. To determine the source of SSBs at neuro
NIAID Data Ecosystem50
Somatic DNA demethylation generates tissue-specific methylation states and impacts flowering time [BiSulfite-seq]
Cytosine methylation is a reversible epigenetic modification to DNA. In plants, removal of cytosine methylation is accomplished by the four members of the DME family of 5-methylcytosine DNA glycosylas
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