Motif analysis of enriched gene lists.

The table represents significantly enriched transcription factor binding motifs, with the P-Value and the Bonferroni P-Value. Gene lists from ChIP-chip analyses were analyzed for enrichment of transcription factor binding sites (motifs) using Pscan [22]. The analysis of promoters of enriched genes showed an enrichment of the ETS binding motif GGAA/T in the primary samples for the region −950 to +50 bp with regard to the transcription start site (TSS). AML B and the HL60 negative control were not enriched for ETS binding motifs. Furthermore, AML D and T-ALL showed an additional enrichment for further TF binding motifs.