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CryoEM structure of MDA5-dsRNA filament in complex with ADP with 92-degree helical twist

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Protein Data Bank Japan2024-07-10 更新2026-04-19 收录
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CryoEM structure of MDA5-dsRNA filament in complex with ADP with 92-degree helical twist Descriptor: ADENOSINE-5'-DIPHOSPHATE, Isoform 2 of Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ... Authors: Yu, Q, Modis, Y. Deposit date: 2021-01-17 Release date: 2021-11-17 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA. Nat Commun, 12, 2021
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2021-01-17
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