Angiotensinogen and C3 compete for renin-induced complement activation

NIAID Data Ecosystem2026-05-02 收录

肾素-补体交叉调控

补体激活机制

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https://www.omicsdi.org/dataset/pride/PXD053116 数据链接链接失效反馈

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Demonstration of renin cleavage of C3. Angiotensinogen and C3 compete for renin-induced complement activation.

创建时间：

2025-04-18

Model of gC1q-Fc complex based on 7A EM map

补体激活机制

蛋白质复合物结构解析

Model of gC1q-Fc complex based on 7A EM map Descriptor: Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, ... Authors: Ugurlar, D, Ho

Protein Data Bank Japan2024-11-13 更新80

Defining the Structural Features of Complement-Active IgM: Surface Ag linker comparison

抗体结构功能

补体激活机制

Immunoglobulin mu (IgM) is a class of mammalian antibodies that are critical for the early stages of adaptive immunity and are the most potent activators of the classical complement cascade. While the

NIAID Data Ecosystem50

Complement system does not activate on fibrin surfaces.

补体激活机制

纤维蛋白免疫调节

A: Formation of C3a in 2.5% serum incubated in wells coated with fibrin, the known complement activators heat aggregated immunoglobulin (HAIgG) and mannan, and the negative control BSA. The assay was

Figshare2016-02-23 更新30

IL1β-dependent extravasation of pre-existing lung-restricted autoantibodies activates complement to promote primary graft dysfunction

肺移植免疫反应

补体激活机制

Pre-existing lung restricted autoantibodies (LRA) are associated with a higher incidence of primary graft dysfunction (PGD) although it remains unclear whether LRA can drive its pathogenesis. In synge

NIAID Data Ecosystem70

Non-specific adsorption of complement proteins affects complement activation pathways of gold nanomaterials

纳米免疫毒性

补体激活机制

The complement system is a key humoral component of innate immunity, serving as the first line of defense against intruders, including foreign synthetic nanomaterials. Although gold nanomaterials (AuN

Figshare2017-04-27 更新30

Angiotensinogen and C3 compete for renin-induced complement activation

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