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Decoding stimulus-specific regulation of promoter activity of p53 target gene...

B2FIND2026-04-30 收录

p53信号通路调控

单分子RNA定量分析

数据链接：

https://b2find.eudat.eu/dataset/93be21b4-5e61-5bb7-98a4-1410b9039b58 数据链接链接失效反馈

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资源简介：

All measurements derived from smFISH experiments as well as additional output from Bayesian inference are publicly available via the institutional repository of Technical...

应用场景：

肿瘤微生物组

p53信号通路调控

Increasing evidence highlights the role of bacteria in the physiopathology of cancer. However, the underlying molecular mechanisms remains poorly understood. Several cancer-associated bacteria have be

NIAID Data Ecosystem50

RFX7, ANKRA2, and p53-regulated transcriptome in RPE-1. RFX7, ANKRA2, and p53-regulated transcriptome in RPE-1

p53信号通路调控

转录组学分析

Identification of the RFX7-regulated transcriptome in Nutlin-3a and DMSO control treated RPE-1 cells Overall design: RNA-seq (PolyA) from Nutlin-3a and DMSO control treated RPE-1 cells transfected wit

NIAID Data Ecosystem30

Chemotherapeutic Sensitization of Leptomycin B Resistant Lung Cancer Cells by Pretreatment with Doxorubicin

肿瘤耐药性逆转

p53信号通路调控

The development of novel targeted therapies has become an important research focus for lung cancer treatment. Our previous study has shown leptomycin B (LMB) significantly inhibited proliferation of l

NIAID Data Ecosystem20

Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos

p53信号通路调控

斑马鱼发育

DNA damage-binding protein 1 (DDB1) is a large subunit of the heterodimeric DDB complex that recognizes DNA lesions and initiates the nucleotide excision repair process. DDB1 is also a component of th

NIAID Data Ecosystem40

PATZ1 is a DNA damage responsive transcription factor that inhibits p53 function. Mus musculus

p53信号通路调控

转录因子功能基因组学

Insults to cellular health cause p53 protein accumulation and loss of p53 function leads to tumorigenesis. Thus, p53 has to be tightly controlled. Here we report that the BTB/POZ domain transcription

NIAID Data Ecosystem30

Decoding stimulus-specific regulation of promoter activity of p53 target gene...

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