ASINA Dataset: LC2_σ_Ηuman lung_real dose

From the exposure campaigns (10.5281/zenodo.16641460) the alveolar retained doses (μg/cm²) from Multiple-path particle dosimetry (MPPD) model (10.5281/zenodo.16642495) were then translated into real occupational exposure doses and tested in Tier 2 advanced in vitro models, using A549 cells co-cultured with alveolar macrophages derived from THP-1 monocytes (Motta et al. 2024). σ_Ηuman lung_real dose.xlsx dataset includes physicochemical properties, and biological responses of NM (not NEP_ID), supporting hazard evaluation. Biological responses assess NM effects on the cell lines under exposure conditions (ng/cm², h). Cytotoxicity is measured via lactate dehydrogenase (LDH) release (%), while inflammatory responses are evaluated through fold changes in pro-inflammatory cytokines, including Interleukins 8, 6 and 1β (IL-8, IL-6, IL-1β).