Variants in Candidate Genes and their Interactions with Smoking on the Risk of Acute Coronary Syndrome

The data correspond to genetic variants related to inflammation, lipid metabolism, and platelet aggregation of subjects from northeast Colombia, and the covariables age, sex, education level, percentage of European ancestry, smoking, diabetes, arterial hypertension, dyslipidemia, and socioeconomic status.

We obtained these data to investigate candidate genes' association with Acute Coronary Syndrome (ACS). Furthermore, to evaluate the effects of interactions between polymorphisms and smoking on Acute Coronary Syndrome.
The genetic variants are:
rs11206510
rs646776
rs599839
rs1800872
rs1800896
rs1799964
rs3798220
rs10455872
rs2227631
rs2230806
rs579459
rs501120
rs1746048
rs964184
rs1861493
rs5918
rs6511720
rs429358
rs7412
rs4420638
The data set is PLINK standard format(1), and it is compounded by the following files: ACS.ped, ACS.map, ACScovariables.txt, Dictionary.txt (Dictionary of variables)

1. Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, Bender D, Maller J, Sklar P, Bakker PIW de, Daly MJ et al. (2007) PLINK: A tool set for whole-genome association