Helicenes are high interest synthetic targets with unique conjugated helical structures that have found important technological applications. Despite this interest, helicenes have had limited impact i
To utilize the unique scaffold of a natural product indirubin, we herein adopted the strategy of combined pharmacophores to design and synthesize a series of novel indirubin derivatives as dual inhibi
Retrofitting antibodies with stabilizing mutations. Herceptin scFv mutant. Descriptor: Human Variable Heavy Chain of Herceptin, Human Variable Light Chain of Herceptin Authors: Langley, D.B, Roome, B,
