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The rates of BIR-associated mutagenesis in various <i>pif1</i>-deficient mutants.

NIAID Data Ecosystem2026-05-01 收录

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https://figshare.com/articles/dataset/The_rates_of_BIR-associated_mutagenesis_in_various_pif1-deficient_mutants_/23738836 数据链接链接失效反馈

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The rates of BIR-associated mutagenesis in various pif1-deficient mutants.

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创建时间：

2023-07-24

断裂诱导复制

复杂染色体重排

DNA double-strand break (DSB) repair occurring in repeated DNA sequences often leads to the generation of chromosomal rearrangements. Homologous recombination normally ensures a faithful repair of DSB

NIAID Data Ecosystem90

DNA Polymerase delta synthesizes both strands during break-induced replication

断裂诱导复制

DNA聚合酶delta功能

In this study, the efficiency of break-induced replication was measure by physical assays (PCR or Southern blot hybridization of genomic DNA) in wild type (WT) and cells with mutations in each of the

NIAID Data Ecosystem30

EXO1 and SGS1 inhibit BIR.

断裂诱导复制

aThe percent BIR was determined by the number of stable Ura+ colonies divided by the number of Ura+ colonies at 24 hr normalized to the percent Ura+ at 0 hr. bAll fold differences are calculated with

NIAID Data Ecosystem20

Investigation of impact of DNA synthesis during Break-induced replication on transcription. Investigation of impact of DNA synthesis during Break-induced replication on transcription

断裂诱导复制

转录调控

We discovered that during rPolII is enriched in the TES region due colision between transcription and BIR synthesis. This enrichment is specific to genes that are located in head-on orientation to BIR

NIAID Data Ecosystem80

Break-induced replication: A review and an example in budding yeast

断裂诱导复制

基因组完整性

Break-induced replication (BIR) is a nonreciprocal recombination-dependent replication process that is an effective mechanism to repair a broken chromosome. We review key roles played by BIR in mainta

PubMed Central2001-07-17 更新30

The rates of BIR-associated mutagenesis in various <i>pif1</i>-deficient mutants.

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