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IkBNS-deficiency protects mice from Listeria monocytogenes infection by blunting pro-inflammatory signature in Ly6Chigh monocytes and preventing exaggerated innate immune responses

NIAID Data Ecosystem2026-03-14 收录

李斯特菌感染免疫机制

细胞炎症反应

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE220267 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-01-13

巨噬细胞免疫调节

细胞炎症反应

This experiment explored the impact of cell volume increase and regulatory volume decrease (RVD) on the transcriptome of mouse macrophages. Bone marrow-derived macrophages (BMDMs) were isolated from

NIAID Data Ecosystem80

Systematic analysis of the pro and anti-inflammatory activation of mouse myeloid cells

细胞炎症反应

骨髓细胞RNA-seq分析

Inflammation is a fundamental physiological process and a key line of defense against pathogen invasion. Inflammation is exquisitely controlled: Too high and inflammation can be dangerous to the organ

NIAID Data Ecosystem60

Effect of Aeroplysinin-1 on gene expression in Murine RAW264.7 macrophages in basal and LPS stimulated conditions (2hours)

药物基因调控

细胞炎症反应

To determine the effect of Aeroplysinin-1 (Ap) on gene expression, we treated murine RAW264.7 macrophages (ATCC TIB-71) with DMSO control or Aeroplsinin-1 (1uM) for 2 hours. Unstimulated and LPS stimu

科学数据银行2024-03-12 更新40

Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells.

表观遗传调控

细胞炎症反应

Histone H3 lysine-9 di-methylation (H3K9me2) and lysine-27 tri-methylation (H3K27me3) are linked to repression of gene expression, but the functions of repressive histone methylation dynamics during i

NIAID Data Ecosystem80

Differential gene expression profiles by septin 2 suppression and TNF-a treatment in human microvascular endothelial cells

基因表达调控

细胞炎症反应

Arrangements of juntional proteins of endothelial monolayers were altered by both septin 2 KD and TNF-a treatment. Therefore, differential gene expression profiles by septin 2 KD comapred to control a

NIAID Data Ecosystem50

IkBNS-deficiency protects mice from Listeria monocytogenes infection by blunting pro-inflammatory signature in Ly6Chigh monocytes and preventing exaggerated innate immune responses

资源简介：

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