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Transcriptomics data of blood and brain from the YAC128 Huntington's disease mouse model. Transcriptomics data of blood and brain from the YAC128 Huntington's disease mouse model

NIAID Data Ecosystem2026-03-12 收录

亨廷顿病转录组

YAC128小鼠模型

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA718063 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2021-03-28

亨廷顿病转录组

单细胞核差异表达

Additional file 16. Differential gene expression between control and HD neuronal nuclei, GO term enriched in top differentially upregulated and downregualted genes.

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mRNA Sequencing of control and huntington's disease iPSC-derived medium spiny neuron-like cells and Q175 HET or WT mice. Plus and minus knockdown of PIAS1.

亨廷顿病转录组

PIAS1基因功能

HD and control patient-derived induced pluripotent stem cells were used to generate medium spiny neuron-like cells. four control in duplicate and three HD samples in duplicate with CAG repeat length

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Effect of IL-6 deficiency on gene expression in cell types of control and HD mouse striatum

亨廷顿病转录组

IL-17免疫调节

Huntington's disease (HD) is an incurable neurodegenerative disorder that is caused by CAG trinucleotide expansions in the huntingtin gene. However, the exact molecular and cellular mechanisms underly

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Striatal gene expression data from 12 weeks-old R6/2 mice and control mice (set 2). Mus musculus

亨廷顿病转录组

小鼠模型基因表达

To test the hypotheses that mutant huntingtin protein length and wild-type huntingtin dosage have important effects on disease-related transcriptional dysfunction, we compared the changes in mRNA in s

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RNA-seq: Analysis of differential gene expression between HD and DM1 patient lymphoblastoid cell lines (LCLs) compared to unaffected LCLs.. RNA-seq: Analysis of differential gene expression between HD and DM1 patient lymphoblastoid cell lines (LCLs) compared to unaffected LCLs.

亨廷顿病转录组

强直性肌营养不良转录组

Transcriptome from HD, DM1, and unaffected LCLs. Overall design: Data from two unaffected LCLs: GM04604 (UN-B) and GM02180 (UN-C). From three HD patient LCLs: GM02164 (HD-A), GM03620 (HD-B), and GM140

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Transcriptomics data of blood and brain from the YAC128 Huntington's disease mouse model. Transcriptomics data of blood and brain from the YAC128 Huntington's disease mouse model

资源简介：

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