PDGFRb+ Mesenchymal Cells, but Not NG2+ Mural Cells, Contribute to Cardiac Fat
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We performed lineage tracing studies using various genetic models, and found that cardiac mesenchymal cells (MCs) contribute to CAs in postnatal development and adulthomeostasis. Moreover, we found that PDGFRb+ cells are heterogenous, and revealed that PDGFRa+PDGFRb+ double-positive periendothelial fibroblasts contribute to intramyocardial adipocytes. In contrast, SMCs and NG2+ pericytes did not contribute to CAs. We performed single cell RNA sequencing to compare the heterogeneity
创建时间：
2020-07-09
