New Strategy for the Synthesis of Tetrahydroisoquinoline Alkaloids
收藏NIAID Data Ecosystem2026-03-06 收录
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A general strategy for the formation of 1,3-cis-substituted tetrahydroisoquinolines is described from ortho-iodo imines involving Larock isoquinoline synthesis, addition of organolithium compounds to unactivated isoquinolines, and ionic hydrogenation. In addition, a new synthesis of lactams via an unprecedented azide cyclization in the presence of a sulfonium ion is described.
创建时间：
2016-08-20
