A Diastereoselective Multicomponent Reaction for Construction of Alkynylamide-Substituted α,β-Diamino Acid Derivatives To Hunt Hits
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下载链接：
https://figshare.com/articles/dataset/A_Diastereoselective_Multicomponent_Reaction_for_Construction_of_Alkynylamide-Substituted_-Diamino_Acid_Derivatives_To_Hunt_Hits/4725853
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资源简介：
A highly diasetereoselective
Mannich-type multicomponent reaction
was developed to rapidly construct alkynylamide-substituted α,β-diamino
acid derivatives from simple starting materials under mild conditions
in moderate to good yields for hit hunting. Most of the resulting
products 4 exhibited good anticancer activity in HCT116,
BEL7402, and SMMC7721 cells.
创建时间：
2017-03-06
