A new MCM modification cycle regulates DNA replication initiation

Alliance of Genome Resources2026-08-01 收录

DNA复制调控

MCM解旋酶修饰

数据链接：

https://www.yeastgenome.org/dataset/GSE70407 数据链接链接失效反馈

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资源简介：

The hexameric DNA helicase MCM (Mcm2-7) is a central regulatory target in eukaryotic replication

GSE20887: ORC2 S2-DSRC ChIP-Seq experiment. GSE20887: ORC2 S2-DSRC ChIP-Seq experiment

ChIP-seq数据分析

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Summary: modENCODE_submission_2753

NIAID Data Ecosystem30

Replication and Protein binding profile of chromosome VI of S.cerevisiae. Saccharomyces cerevisiae

DNA复制调控

染色质免疫沉淀芯片分析

Type of experiment: ChIP-chip (Chromatin immunoprecipitation on DNA chip) analyses of replication related, checkpoint related proteins and BrdU incorporated regions at 300bp resolution. Newly develope

NIAID Data Ecosystem20

Identification of cis elements for temporal and spatial control of DNA replication [Capture Hi-C]

DNA复制调控

染色体三维结构

DNA replication occurs in units of chromatin higher order organization (Topologically Associating Domains, or TADs; replication domains, or RDs), which self-organize in 3D into sub-nuclear compartment

NIAID Data Ecosystem10

In vivo protein-DNA interactions at human DNA replication origin.

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DNA相互作用

Protein-DNA interactions were studied in vivo at the region containing a human DNA replication origin, located at the 3' end of the lamin B2 gene and partially overlapping the promoter of another gene

PubMed Central1996-02-20 更新30

The fission yeast homologue of Orc4p binds to replication origin DNA via multiple AT-hooks

DNA复制调控

DNA相互作用

The origin recognition complex (ORC) was originally identified in the yeast Saccharomyces cerevisiae as a protein that specifically binds to origins of DNA replication. Although ORC appears to play an

PubMed Central1999-03-16 更新10

A new MCM modification cycle regulates DNA replication initiation

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