Structure of human STING in complex with MK-1454
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Structure of human STING in complex with MK-1454 Descriptor: (2R,5R,7R,8S,10R,12aR,14R,15S,15aR,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-15,16-difluoro-2,10-bis(sulfanyl)octahydro-2H,10H,12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein Authors: Lesburg, C.A. Deposit date: 2021-04-15 Release date: 2022-04-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.32 Å) Cite: A kinase-cGAS cascade to synthesize a therapeutic STING activator. Nature, 603, 2022
创建时间：
2021-04-15
