MLL-Menin inhibition reverses pre-leukemic progenitor self-renewal induced by NPM1c mutations [ChIP-Seq]
收藏NIAID Data Ecosystem2026-05-02 收录
下载链接：
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE129636
下载链接
链接失效反馈官方服务：
资源简介：
Menin binding to MLL1 is required to maintain self-renewal properties of NPM1c progenitors at different stages of leukemia development Mouse NPM1c knock-in cells and human AML cell lines carrying NPM1c mutations were analyzed for the gene expression changes induced by NPM1c and in response to Menin inhibitor VTP-50469.
创建时间：
2025-07-30
