Characterization of the effect of deleting the Nrg-1(neuregulin-1) gene, using the tamoxifen-inducible endothelial driver line Cdh5-CreERT in E (embryonic day) 15.5 hearts
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https://www.ncbi.nlm.nih.gov/sra/SRP404270
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To investigate the role of Nrg-1 in heart ventricular chamber development, we induced a conditional Nrg-1 deletion in endothelial cells at E15.5, with tamoxifen, and determined gene expression profiles, using RNA-seq. Overall design: Gene expression profiling with RNA-seq was performed on 4 replicate samples of control (WT) and 4 replicate samples of mutant (Nrg-1flox;Cdh5-CreERT2) (1 ventricle per replicate) at E15.5
创建时间:
2025-07-04



