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Foxo1 nuclear exclusion preferentially promotes CD8 T cell survival over memory T cell differentiation

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NIAID Data Ecosystem2026-03-11 收录
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Investigation of how phosphorylation at Foxo1 S209 regulates effector versus memory CD8 T cell differentiation. We generated Foxo1 variants in which S209 was mutated to alanine (S209A, SA) or aspartic acid (S209D, SD) to determine how Foxo1 behaves in the non-phosphorylated or phosphorylated state, respectively.

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2020-02-25
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