Conformational plasticity across phylogenetic clusters of RND multidrug efflux pumps and its impact on substrate specificity

AcrB_wt_apo_DDM:
Single particle cryo-EM maps (.mrc) of trimeric AcrB wildtype in DDM (apo-state)

AcrB_wt_apo_SP-ND:
Single particle cryo-EM maps (.mrc) of trimeric AcrB wildtype in SaliPro-nanodiscs (apo-state)

V612F_apo_DDM:
Single particle cryo-EM maps (.mrc) of trimeric AcrB V612F variant in DDM (apo-state)

V612F_apo_SP-ND:
Single particle cryo-EM maps (.mrc) of trimeric AcrB V612F variant in SaliPro-nanodiscs (apo-state)

V612W_apo_DDM:
Single particle cryo-EM maps (.mrc) of trimeric AcrB V612W variant in DDM (apo-state)

OqxB_apo_SP-ND:
Single particle cryo-EM maps (.mrc) of trimeric OqxB wildtype in SaliPro-nanodiscs (apo-state)

In total:
AcrB wt DDM - 3 maps
AcrB wt SP-ND - 16 maps
V612F DDM - 3 maps
V612F SP-ND - 4 maps
V612W DDM - 6 maps
OqxB wt SP-ND - 6 monomer maps + 1 trimer map
in sum: 39 .mrc files