Role of interleukin-4 in the licensing of dendritic cells for the induction of Th2 responses

NIAID Data Ecosystem2026-03-07 收录

树突状细胞免疫调控

Th2免疫应答诱导

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA171884 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

创建时间：

2012-08-03

PPARa Inhibition Overcomes Tumor Derived Exosomal Lipids-Induced Dendritic Cell Dysfunction

免疫逃逸机制

树突状细胞免疫调控

Dendritic cells orchestrate the initiation, programming, and regulation of anti-tumor immune responses. Emerging evidence indicates that the tumor microenvironment (TME) induces immune dysfunctional t

NIAID Data Ecosystem70

PTBP1 is necessary for dendritic cells to regulate T cells homeostasis and antitumor immunity

树突状细胞免疫调控

肿瘤免疫治疗靶点

Dendritic cells (DCs) play an important role in innate and adaptive immunity. DCs could sense environment pathogens and tumors, presenting those antigens to T cells. PTBP1, an RNA-binding protein, the

NIAID Data Ecosystem60

IFN-III primes pDCs for TLR7 activation and antagonizes TGF-β mediated-immune suppression in tumors.

肿瘤免疫微环境

树突状细胞免疫调控

Conventional dendritic cell (cDC1, cDC2) and plasmacytoid dendritic cell (pDCs) subsets have specialized functions that can be modulated by the tumor microenvironment (TME). These cells produce differ

NIAID Data Ecosystem30

Effect of depletion of Zeb1 in CD11c+ dendritic cells. Effect of depletion of Zeb1 in CD11c+ dendritic cells

树突状细胞免疫调控

基因表达谱分析

To investigate potential target genes of Zeb1 that were involved in regulation of antigen cross-presentation. We then performed gene expression profiling analysis using data obtained from RNA-seq from

NIAID Data Ecosystem60

Title: An IL-23-STAT4 Axis Regulates Classical Dendritic Cell Expansion and Function in Experimental Autoimmune Encephalomyelitis

自身免疫性疾病

树突状细胞免疫调控

The signal transducer and activator of transcription 4 (STAT4) promotes protective immunity and autoimmunity downstream of pro-inflammatory cytokines including IL-12 and IL-23. In experimental autoimm

NIAID Data Ecosystem40

Role of interleukin-4 in the licensing of dendritic cells for the induction of Th2 responses

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