An siRMSD parameter of structural distortion induced by chemical modification is predictive of the off-target effect of siRNA_(1/2)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE278438
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资源简介：
To investigate effects of siRNA with various 2'-ribose modifications on genome-wide off-target effect, we analyzed gene expression profile of HeLa cells transfected by their siRNAs. Total RNAs were extracted from HeLa cells transfected by mock, unmodified, 2'-formamido, 2'-deoxy, or 2'-O-methoxyethyl modified siRNA and performed microarray analysis.
创建时间：
2025-09-16
