Supplementary Table S5 from Immunogenomics of Hypermutated Glioblastoma: A Patient with Germline POLE Deficiency Treated with Checkpoint Blockade Immunotherapy

DNA repair pathway mutations found in the founding clone (Cluster 1). Gene list was derived from http://sciencepark.mdanderson.org/labs/wood/dna_repair_genes.html, and annotated with data from ClinVar (www.ncbi.nlm.nih.gov/clinvar/), COSMIC http://cancer.sanger.ac.uk/cosmic), the Foundation Medicine report provided to this patient, and SIFT/PolyPhen predictions from ExAC (http://exac.broadinstitute.org/).