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Spatial Pyramid Pooling (SPP) is important in capturing remote contextual information for pixel-level prediction tasks in scene-resolved detection of rice diseases. In this paper, the detection objects of the rice disease dataset used in this paper have almost the same target size and do not need to be passed through different filters to obtain different receptive fields of view. Therefore, this paper proposed a new pooling structure, SPPFCSPC-G, which split the feature vector into 2 channels for processing. One channel was processed using grouped 1×1 Conv, while the other channel mainly used multiple filters with the same parallel structure (5×5 MaxPool). Additionally, multiple 1×1 and 3×3 grouped convolutions were concatenated in series in that branch (Group-Conv) to extract more complex features in rice. Finally, the 2 parts were connected (Concat) together, with each convolutional layer Conv divided into 4 groups as a way to reduce the amount of computation in the model. The project team incorporated SPPFCSPC-G into the Backbone of YOLOv5 and trained it on NVIDIA Tesla T4 (GPU). The experimental results showed that the performance of the method used in this paper improved, including Precision, Recall, mAP, and training speed, while reducing the size of computational parameters (Parameters), computational volume (GFLOPs), and model size (Param.). The project team carried out the trained YOLOv5 model on Intel Core i5 (CPU) for inference detection of rice leaves in real scenarios, and the experiments showed that both pre-inference and actual inference were faster. Moreover, the consumption of computational resources was almost minimized, and the model effectively identified rice diseases.