SEMA7A binds to PLXNC1

Sema7A signals through two unrelated receptors, an RGD-dependent alpha1beta1-integrin and a member of the plexin family, plexinC1. Sema7A-plexinC1 interactions have been implicated in immune system function and also participate in neuronal network formation.

Sema7A 信号通过两种无关的受体进行传递，分别为依赖 RGD 的 alpha1beta1 整合素以及 plexin 家族成员 plexinC1。Sema7A 与 plexinC1 的相互作用已被证实与免疫系统功能密切相关，并参与神经元网络的构建。