Cut&tag sequencing of bovine ovarian granulosa cells

Changes in histone acetylation can affect transcriptional activation and inhibition of target genes. To explore the potential function of H4K8ac abundance changes caused by acetyl-CoA fluctuations caused by SUCLG2 succinylation in bovine ovarian granulosa cells, we used CUT & Tag analysis to determine the downstream regulatory pathway of H4K8ac in granulosa cells. The corresponding sequencing data were obtained in WT, SUCLG2 ( K93 + 101E ) and SUCLG2 ( K93 + 101R ) granulosa cells.